Our research data
Here are some of our notable research data that we captured over the years.
Effectiveness
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Strong
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Notable
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Minor
Supplement Category
Metformin
PRESCRIPTION REQUIRED to receive this product. Aiwo AMet-SR contains Metformin 500mg. Metformin is the first-line oral therapy for diabetes in the recent guidelines of the American Diabetes Association. But it can also lower insulin and blood sugar levels in women with PCOS.
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Liver Health
+AMet-SR increases the body's sensitivity to insulin and it works by lowering glucose production in the liver.
Metformin in non-alcoholic fatty liver disease: A systematic review and meta-analysis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956897/
Therapy for Nonalcoholic Fatty Liver Disease
https://pubmed.ncbi.nlm.nih.gov/18277910/
Evidence That Metformin Exerts Its Anti-Diabetic Effects Through Inhibition of Complex 1 of the Mitochondrial Respiratory Chain
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Heart Health
+AMet-SR can lower LDL (bad) cholesterol, lower blood fat levels, and reduce the risk of heart disease.
Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552849/
Effect of Intensive Glucose Lowering Treatment on All Cause Mortality, Cardiovascular Death, and Microvascular Events in Type 2 Diabetes: Meta-Analysis of Randomised Controlled Trials
https://pubmed.ncbi.nlm.nih.gov/21791495/
Metformin Use Is Associated With a Lower Risk of Hospitalization for Heart Failure in Patients With Type 2 Diabetes Mellitus: a Retrospective Cohort Analysis
https://www.ahajournals.org/doi/10.1161/JAHA.118.011640
Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database
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Anti-oxidant
+AMet-SR is effective in reducing the level of oxidative stress factors.
Metformin attenuates myocardial ischemia-reperfusion injury via up-regulation of antioxidant enzymes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560646//
The Role of Metformin in Controlling Oxidative Stress in Muscle of Diabetic Rats